Marie Scott, 57, was last seen at around 12pm this afternoon (Monday 18 December 2017) on Sandileigh Avenue, Hale.
She is described as 5ft 4ins tall with mid-length blonde hair.
Marie was last seen wearing black leggings with a black bomber jacket.
Inspector Mark Sweeney, of GMP’s Trafford borough, said: “Marie has been missing for over six hours now and her family are understandably very worried about her.
“Please take a good look at the photo and do what you can to help us reunite Marie with her family, who just want her home.”
Anyone with information about Marie’s whereabouts is asked to contact police on 101 quoting MP/17/0111851. Reports can also be made anonymously through the independent charity Crimestoppers on 0800 555 111.